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The Missouri Botanical Garden, founded in 1859, is the oldest continuously operating botanical garden in the country and a National Historic Landmark. The garden’s 79 acres (32 hectares) include an impressive Japanese strolling garden, one of the world’s largest collections of orchids, and some 4,800 trees.
Visitors interested in the history of American music shouldn't miss the National Blues Museum in St. Louis—an institution honoring the legacy of the blues, from field hollers to the recording studio. Exhibits on everything from the form's evolution to famous musicians, plus historic photos and costumes, bring the history to life.